Manitok Catherine Thompson (born 1955 Coral Harbour, Northwest Territories) is a politician from northern Canada.
She was first elected to the Legislative Assembly of Northwest Territories in a by-election held on May 8, 1995 held following the resignation of James Arvaluk. She served the Northwest Territories as the minister of Community and Regional Affairs, until the creation of Nunavut in 1999. In the 1999 Nunavut general election, she was elected as the first member for Rankin Inlet South/Whale Cove until 1999. She served as Nunavut's first female cabinet minister.
She retired from territorial level politics in 2004 and ran as an independent candidate in the 2004 Canadian federal election in Nunavut riding. She finished second.